منابع مشابه
Why is ALS so Difficult to Treat?
Amyotrophic lateral sclerosis (ALS) is proving intractable. Difficulties in pre-clinical studies contribute in small measure to this futility, but the chief reason for failure is an inadequate understanding of disease pathogenesis. Many acquired and inherited processes have been advanced as potential causes of ALS but, while they may predispose to disease, it seems increasingly likely that none...
متن کاملArchitectural Mismatch: Why Reuse Is So Hard
This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyrig...
متن کاملWhy Is Cartographic Generalization So Hard?
Why Is Cartographic Generalization So Hard? Andrew U. Frank Department for Geoinformation and Cartography Gusshausstrasse 27-29/E-127-1 A-1040 Vienna, Austria [email protected]
متن کاملArchitectura Mismatch : Why Reuse Is So Hard
my isn't there more progress toward building systems f+om existing parts? One ansueT is that the assumptions of the parts about their intended environment are implicit and either don't match the actual environment oy conflict with those of other parts. The authors explore these problems in the context of their own experience with a compositional approach. F uture breakthroughs in software produ...
متن کاملClinical terminology: why is it so hard?
Despite years of work, no re-usable clinical terminology has yet been demonstrated in widespread use. This paper puts forward ten reasons why developing such terminologies is hard. All stem from underestimating the change entailed in using terminology in software for 'patient centred' systems rather than for its traditional functions of statistical and financial reporting. Firstly, the increase...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science
سال: 2012
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.338.6103.32